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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 4
1991 1
1993 3
1994 4
1995 4
1996 4
1997 4
1998 8
1999 4
2000 6
2001 11
2002 7
2003 1
2004 4
2005 4
2006 2
2007 6
2008 3
2009 3
2010 6
2011 2
2012 4
2013 2
2014 3
2015 4
2016 3
2017 1
2018 4
2019 1
2021 1
2022 5
2023 4
2024 2

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115 results

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Page 1
Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.
Zhou J, Liu M, Sun H, Feng Y, Xu L, Chan AWH, Tong JH, Wong J, Chong CCN, Lai PBS, Wang HK, Tsang SW, Goodwin T, Liu R, Huang L, Chen Z, Sung JJ, Chow KL, To KF, Cheng AS. Zhou J, et al. Gut. 2018 May;67(5):931-944. doi: 10.1136/gutjnl-2017-314032. Epub 2017 Sep 22. Gut. 2018. PMID: 28939663 Free PMC article.
Concordant overexpression of CCRK and MDSC markers (CD11b/CD33) positively correlated with poorer survival rates. Hepatocellular CCRK stimulated immunosuppressive CD11b(+)CD33(+)HLA-DR(-) MDSC expansion from human peripheral blood mononuclear cells through upregulat …
Concordant overexpression of CCRK and MDSC markers (CD11b/CD33) positively correlated with poorer survival rates. Hepatocellular CCRK …
Neuroinflammation, its Role in Alzheimer's Disease and Therapeutic Strategie.
Kiraly M, Foss JF, Giordano T. Kiraly M, et al. J Prev Alzheimers Dis. 2023;10(4):686-698. doi: 10.14283/jpad.2023.109. J Prev Alzheimers Dis. 2023. PMID: 37874089
Broad-scale unbiased genomic studies bring several genetic variants such as sialic acid binding Ig-like lectin 3 (CD33), triggering receptor expressed on myeloid cells 2 (TREM2) or complement receptor type 1 (CR1) into the f …
Broad-scale unbiased genomic studies bring several genetic variants such as sialic acid binding Ig-like …
CD33 is downregulated by influenza virus H1N1pdm09 and induces ROS and the TNF-alpha, IL-1beta, and IL-6 cytokines in human mononuclear cells.
Guzmán-Beltrán S, Herrera MT, Torres M, Gonzalez Y. Guzmán-Beltrán S, et al. Braz J Microbiol. 2022 Mar;53(1):89-97. doi: 10.1007/s42770-021-00663-4. Epub 2022 Jan 24. Braz J Microbiol. 2022. PMID: 35075617 Free PMC article.
A pathway by which spontaneous TNF-alpha production occurs involves either the reduction of Siglec-3 (CD33) levels or the absence of its ligand, sialic acid. Influenza virus uses sialic acid to enter cells by reducing their expression; however, the role of CD33 in I …
A pathway by which spontaneous TNF-alpha production occurs involves either the reduction of Siglec-3 (CD33) levels or the absence of …
Gemtuzumab ozogamicin.
McGavin JK, Spencer CM. McGavin JK, et al. Drugs. 2001;61(9):1317-22; discussion 1323-4. doi: 10.2165/00003495-200161090-00007. Drugs. 2001. PMID: 11511025 Review.
Gemtuzumab ozogamicin is a humanised monoclonal IgG4 antibody, linked to a cytotoxic calicheamicin derivative. It effects cell necrosis by specifically targeting the CD33 antigen which is expressed on the surface of leukaemic cell blasts in more than 90% of patients …
Gemtuzumab ozogamicin is a humanised monoclonal IgG4 antibody, linked to a cytotoxic calicheamicin derivative. It effects cell necrosis …
TNFalpha induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes.
Iriani A, Rachman A, Setiabudy RD, Kresno SB, Sudoyo AW, Arief M, Harahap AR, Fatina MK. Iriani A, et al. BMC Mol Cell Biol. 2023 Nov 21;24(1):33. doi: 10.1186/s12860-023-00495-0. BMC Mol Cell Biol. 2023. PMID: 37990142 Free PMC article.
This study aims to establish the role of TNFalpha exposure in triggering apoptosis through caspase-3 activity in CD34+, CD33+, and CD41 + cells in MDS. METHODS: This study is an in vitro comparative experimental research. ...RESULTS: In MDS CD33 + and CD41 + caspase …
This study aims to establish the role of TNFalpha exposure in triggering apoptosis through caspase-3 activity in CD34+, CD33+, and CD …
The remission status of AML patients after allo-HCT is associated with a distinct single-cell bone marrow T-cell signature.
Mathioudaki A, Wang X, Sedloev D, Huth R, Kamal A, Hundemer M, Liu Y, Vasileiou S, Lulla P, Müller-Tidow C, Dreger P, Luft T, Sauer T, Schmitt M, Zaugg JB, Pabst C. Mathioudaki A, et al. Blood. 2024 Mar 28;143(13):1269-1281. doi: 10.1182/blood.2023021815. Blood. 2024. PMID: 38197505 Free PMC article.
Pseudotime and gene regulatory network analyses revealed that CR CD8+ T cells were more advanced in maturation and had a stronger cytotoxicity signature, whereas REL samples were characterized by inflammatory tumor necrosis factor/NF-kappaB signaling and an immunosuppressi …
Pseudotime and gene regulatory network analyses revealed that CR CD8+ T cells were more advanced in maturation and had a stronger cytotoxici …
Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone-Pyridylhydrazone Copper(II) Complex.
Choo XY, McInnes LE, Grubman A, Wasielewska JM, Belaya I, Burrows E, Quek H, Martín JC, Loppi S, Sorvari A, Rait D, Powell A, Duncan C, Liddell JR, Tanila H, Polo JM, Malm T, Kanninen KM, Donnelly PS, White AR. Choo XY, et al. Int J Mol Sci. 2022 Sep 14;23(18):10722. doi: 10.3390/ijms231810722. Int J Mol Sci. 2022. PMID: 36142627 Free PMC article.
In a primary murine microglia culture, CuL(5) was shown to decrease secretion of pro-inflammatory cytokine macrophage chemoattractant protein 1 (MCP-1) and expression of tumor necrosis factor alpha (Tnf), increase expression of metallothionein (Mt1), and modulate expressio …
In a primary murine microglia culture, CuL(5) was shown to decrease secretion of pro-inflammatory cytokine macrophage chemoattractant protei …
Increased levels of low density neutrophils (LDNs) in myocardial infarction.
Yiu JYT, Hally KE, Larsen PD, Holley AS. Yiu JYT, et al. Acta Cardiol. 2023 Feb;78(1):47-54. doi: 10.1080/00015385.2021.2015145. Epub 2022 Jan 10. Acta Cardiol. 2023. PMID: 35006041
LDNs and NDNs were analysed by flow cytometry to identify neutrophils (CD66b(+)CD15(+)CD14(-)CD3(-)CD19(-) cells) and examine neutrophil activation (CD11b, CD66b and CD15) and maturity (CD33 and CD16). RESULTS: We identified LDNs within the peripheral blood mononuclear cel …
LDNs and NDNs were analysed by flow cytometry to identify neutrophils (CD66b(+)CD15(+)CD14(-)CD3(-)CD19(-) cells) and examine neutrophil act …
CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets.
Gleason MK, Ross JA, Warlick ED, Lund TC, Verneris MR, Wiernik A, Spellman S, Haagenson MD, Lenvik AJ, Litzow MR, Epling-Burnette PK, Blazar BR, Weiner LM, Weisdorf DJ, Vallera DA, Miller JS. Gleason MK, et al. Blood. 2014 May 8;123(19):3016-26. doi: 10.1182/blood-2013-10-533398. Epub 2014 Mar 20. Blood. 2014. PMID: 24652987 Free PMC article.
Blood and marrow MDS-NK cells treated with bispecific killer cell engager (BiKE) significantly enhanced degranulation and tumor necrosis factor-alpha and interferon-gamma production against HL-60 and endogenous CD33(+) MDS targets. ...Our data suggest that the CD16x …
Blood and marrow MDS-NK cells treated with bispecific killer cell engager (BiKE) significantly enhanced degranulation and tumor necrosis …
Peripheral surgical wounding and age-dependent neuroinflammation in mice.
Xu Z, Dong Y, Wang H, Culley DJ, Marcantonio ER, Crosby G, Tanzi RE, Zhang Y, Xie Z. Xu Z, et al. PLoS One. 2014 May 5;9(5):e96752. doi: 10.1371/journal.pone.0096752. eCollection 2014. PLoS One. 2014. PMID: 24796537 Free PMC article.
Abdominal surgery under local anesthesia was established in 9 and 18 month-old mice. The levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), Iba1 positive cells (the marker of microglia activation), CD33, and cognitive function in mice were dete …
Abdominal surgery under local anesthesia was established in 9 and 18 month-old mice. The levels of tumor necrosis factor-alpha (TNF-a …
115 results